Most Replayed Moment: Calories In, Calories Out Is A Myth! Why Most Diets Fail - Dr. Jason Fung

In this episode, the speaker discusses the myths surrounding obesity and weight loss, specifically challenging the traditional calorie in, calorie out model. They argue that basal metabolic rates are not fixed and can adjust to caloric intake, leading to the inefficacy of simple calorie reduction strategies. When individuals diet by eating fewer calories, the body compensates by burning fewer calories, preventing significant weight loss. This phenomenon contributes to the yo-yo dieting effect, where weight returns after a diet is discontinued due to a lowered metabolism.

The conversation emphasizes the importance of understanding hormones that control fat storage and burning, particularly insulin. High insulin levels can prevent the body from accessing stored fat, making it difficult to lose weight even while consuming fewer calories. The speaker advocates for intermittent fasting as a method to help manage insulin levels, allowing the body to burn fat more efficiently. They explain that fasting can activate hormonal responses that increase metabolism, contrasting with typical calorie restriction diets that may decrease metabolic rates.

They also touch on exercise, explaining that while important for overall health, its role in weight loss is limited and can even lead to increased hunger afterward, making weight loss more challenging. The episode concludes with a critique of the modern mentality surrounding breakfast and frequent eating, suggesting that intermittent fasting could be a more effective approach to maintaining health and managing weight.